Class plans[]
- Preliminary plans for the student projects on Genetics were discussed.
- Student contributions on textbook problems, and Concepts & Jargon were presented.
- JMB made a short presentation on conditional mutations, including temperature-sensitive mutants, and nonsense mutants and suppressor tRNA molecules
Assignments for next class[]
- Read Chapter 4
- Work on Genetics project
- Add other content as you are able to do so
Class Notes[]
Reversion - Goes back to normal sequence, where normal is defined as a function of the sequence. Supression - Original mutation is still present but for some reason the suppressor host bypasses the mutation. Usually it is because of a mutant tRNA with a mutant anti-codon arm that can add an amino acid for a stop codon. Identified in bacteria. Stop codons in conditional mutations. Temperature sensitive mutations. Tandem stop codons more common in bacteria.Natural back up plan. suppressor tRNA are not very efficient.